Allow at least 30 minutes between administration of Feraheme and administration of other medications that could potentially cause serious hypersensitivity reactions and/or hypotension, such as chemotherapeutic agents or monoclonal antibodies. Monitor Closely (1)esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Oral and parenteral products - see background option for oral products. Use Caution/Monitor. During all INFeD administrations, observe for signs or symptoms of anaphylactic-type reactions. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Applies only to oral form of both agents. Drug Des Devel Ther; 5: 5160. Minor (2)calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. Information last revised December 2022. Monitor Closely (1)iron sucrose decreases levels of deferiprone by enhancing GI absorption. ONE DOSE. Avoid or Use Alternate Drug. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. All material on this website is protected by copyright, Copyright 1994-2023 by WebMD LLC. Read our. 1974 Jun;31(6):592-5. HONcode standard for trust- worthy health, Pediatric Oncology: Diagnosis And Prognosis Communication. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. May increase risk of hypotension. Recommended dosing and infusion rates for PI. Injection: 50 mg/2.5 mL, 100 mg/5 mL, or 200 mg/10 mL (20 mg/mL) in single-dose vials. Do not double the dose to catch up. Either increases effects of the other by pharmacodynamic synergism. The normal ranges are: for males 13.8 to 18.0 g/dL (138 to 180 g/L, or 8.56 to 11.17mmol/L) and for females 12.1 to 15.1 g/dL (121 to 151 g/L, or 7.51 to 9.37mmol/L). Contraindicated. Parenteral iron supplementation. Calculosaurus | Medical calculators for obstetrics and gynaecology Use the menu to browse through our clinical calculators. This drug is available at the lowest co-pay. Indicated for treatment of iron deficiency anemia associated with chronic kidney disease, Hemodialysis-dependent CKD: 100 mg elemental iron IV (injection or infusion over 2-5 min) per dialysis session not to exceed total cumulative dose of 1000 mg divided in 3 doses/week, Non-dialysis-dependent CKD: 200 mg IV injection for 5 doses in over 14 days (cumulative 1000 mg in 14-day period), Peritoneal dialysis-dependent CKD: 300 mg IV infusion (1.5 hr) for 2 doses 14 days apart, THEN 400 mg IV infusion (2.5 hr) 14 days later (cumulative 1000 mg divided in 3 doses/week), Indicated for maintenance treatment of iron-deficient anemia associated with chronic kidney disease, <2 years: Safety and efficacy not established, Iron replacement treatment in pediatric patients has not been established. Ferrlecit may also be administered undiluted as a slow intravenous injection (at a rate of up to 12.5 mg/min) per dialysis session. Introduction Uses Dosage Warnings Interactions Stability Introduction Hematinic agent; a polynuclear iron (III)-hydroxide sucrose complex. 0.5 mg/kg/min (0.005 mL/kg/min) Maximum infusion rate (if tolerated) Increase to 8 mg/kg/min (0.08 mL/kg/min) Monitor the patient's vital signs throughout the infusion. Iron deficiency anemia calculator (diagnosis), Iron deficiency anemia vs. cimetidine will decrease the level or effect of iron sucrose by increasing gastric pH. Assessing new treatment options. Avoid or Use Alternate Drug. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl [see How Supplied/Storage and Handling (16.2).] By using this form you agree with the storage and handling of your data by this website. Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. Clinical use of the total dose intravenous infusion of iron dextran. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. This site complies with the HONcode standard for trust- worthy health information: verify here. Use Caution/Monitor. iron sucrose increases levels of calcium chloride by enhancing GI absorption. Use Caution/Monitor. Monitor Closely (1)didanosine will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Applies only to oral form of both agents. FERAHEME was non-inferior to Venofer (iron sucrose) in mean Hgb rise from baseline 2,5. The Ganzoni equation is: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron - carboxymaltose); Modify Therapy/Monitor Closely. View the formulary and any restrictions for each plan. Serious - Use Alternative (1)iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. For all products, slow initial infusion is prudent; the patient is observed closely for infusion reactions. Canada residents can call a provincial poison control center. omeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Inspect parenteral drug products visually for the absence of particulate matter and discoloration prior to administration. The recommendation is that most adults need a cumulative dose of elemental iron of at least 1 g. Iron replenishment can be done intravenously, either as total dose (example: iron-dextran or iron carboxymaltose) or as split dose (example: iron sucrose). calcium chloride decreases levels of iron sucrose by inhibition of GI absorption. Applies only to oral form of both agents. Applies only to oral form of both agents. Minor/Significance Unknown. Applies only to oral form of both agents. . Administer Venofer only intravenously by slow injection or by infusion. Evaluate the hematologic response (hemoglobin, ferritin, iron and transferrin saturation) at least one month following the second Feraheme infusion. For males: LBW = 50 kg + 2.3 kg for each inch of patients height over 5 feet For females: LBW = 45.5 kg + 2.3 kg for each inch of patients height over 5 feet. The dose of Ferinject is based on calculation of ideal body weight and calculation of iron deficit using the Ganzoni formula. Iron supplements, regardless of their way of administration, are used to replete body stores and to correct anemia. Serious - Use Alternative (1)iron sucrose decreases levels of eltrombopag by inhibition of GI absorption. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Accessed: 4/12/2011. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Intravenous Injection - PRIOR TO THE FIRST INTRAVENOUS INFeD THERAPEUTIC DOSE, ADMINISTER AN INTRAVENOUS TEST DOSE OF 0.5 ML. Medically reviewed by Drugs.com. There are four variables, all patient parameters, required in the iron deficiency calculator: The patients weight is used in the Ganzoni equation and also when establishing the iron stores. Consult your pharmacist or local waste disposal company. Use Caution/Monitor. Applies only to oral form of both agents. You can further save the PDF or print it. ------------------------------------------------------------------------- Ferric Carboxymaltose [ Injectafer ] Elemental iron: Injectafer contains 50 mg of elemental iron - 750 mg/15 mL [package insert] Indications: Injectafer is indicated for the treatment of iron deficiency anemia in adult patients: who have intolerance to oral iron or have had unsatisfactory response to oral iron; who have non-dialysis dependent chronic kidney disease. 4)Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, Roger SD, Savoia HF, Tampi R, Thomson AR, Wood EM, Robinson KL. Venofer treatment may be repeated if necessary. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Schweiz Med Wochenschr; 100(7):301-3. After administration of iron dextran complex, evidence of a therapeutic response can be seen in a few days as an increase in the reticulocyte count. Avoid or Use Alternate Drug. )If you are using this medication at home, learn all preparation and usage instructions from your health care professional. (See also Notes section. Applies only to oral form of both agents. Your doctor will do laboratory tests to monitor your response. Applies only to oral form of both agents. USES: This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. The dosage of Venofer is expressed in mg of elemental iron. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. Bhowmik D, Modi G, Ray D, Gupta S, Agarwal SK, Tiwari SC, Dash SC. ]Venofer treatment may be repeated if iron deficiency reoccurs. Dosing Administration & Considerations . informational and educational purposes only. Administer on 5 different occasions over a 14 day period. To provide clinicians with evidence-based guidance for iron therapy dosing in patients with iron deficiency anemia (IDA), we conducted a study examining the benefits of a higher cumulative dose of intravenous (IV) iron than what is typically administered. ------------------------------------------------------------------------- Iron Dextran Complex [ Infed ] Elemental iron: 50 mg of elemental iron per mL [2 mL] [package insert] BOXED WARNING: WARNING: RISK FOR ANAPHYLACTIC-TYPE REACTIONS Anaphylactic-type reactions, including fatalities, have followed the parenteral administration of iron dextran injection. Applies only to oral form of both agents. You may report side effects to Health Canada at 1-866-234-2345. All you have to do is use the following formula: Liquid\ dose = Dose / Medicine\ concentration Liquid dose = Dose/M edicine concentration. IDA symptoms vary, may not be specific and include tiredness, weakness, shortness of breath. Use Caution/Monitor. A healthcare provider will give you this injection. This topic . Applies only to oral form of both agents. sodium citrate/citric acid will decrease the level or effect of iron sucrose by increasing gastric pH. Venofer (Iron Sucrose Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Treatment of iron deficiency anemia associated with gastrointestinal tract diseases, Diagnosis and management of iron deficiency anaemia: a clinical update. For additional Safety Information, please see Full Prescribing Information. Equations used: 1] Calculation of the Total Iron Deficit: Total iron deficit [mg] = body weight [kg] x (target Hb-actual Hb) [g/dl] x 2.4 + depot iron [mg]. Brand name: Venofer Drug class: Iron Preparations Chemical name: iron saccharate CAS number: 8047-67-4 Medically reviewed by Drugs.com on Oct 25, 2022. VENOFER at IV doses up to 15 mg iron/kg/dose [about 10 times the maximum recommended human dose for a 70 kg person] given three times a week was found to have no effect on fertility . sodium bicarbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Volume of iron sucrose needed = 60 x (14 - 8) x (2.145) 20 = 38.6 mL . Monitor Closely (1)deferoxamine decreases levels of iron sucrose by inhibition of GI absorption. Separate dosing of tetracyclines from these products. Monitor Closely (1)dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Avoid or Use Alternate Drug. Applies only to oral form of both agents. Untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia. In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron carboxymaltose); Iron deficiency is common during childhood growth, prolonged periods of sickness, in convalescence or during pregnancy. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Kidney Int. 1988 May;111(5):566-70. Either decreases levels of the other by inhibition of GI absorption. 1970;100(7):301303. Applies only to oral form of both agents. calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. Use alternatives if available. *Repeat dose if iron deficiency anemia reoccurs. iron sucrose decreases levels of manganese by inhibition of GI absorption. Minor (1)iron sucrose decreases levels of manganese by inhibition of GI absorption. Either increases effects of the other by pharmacodynamic synergism. Your doctor will do laboratory tests to monitor your response. Nutr Clin Pract. Applies only to oral form of both agents. Monitor Closely (1)trientine, iron sucrose. Slowing the infusion rate may alleviate symptoms. Minor/Significance Unknown. dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. Venofer® (iron sucrose) injection, USP is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=abacb7fa-2fc2-471e-9200-944eeac8ca2a. Use Caution/Monitor. Minor (2)calcium chloride decreases levels of iron sucrose by inhibition of GI absorption. Serum iron, total iron binding capacity (TIBC) and percent saturation of transferrin are other important tests for detecting and monitoring the iron deficient state. Severe adverse reactions including circulatory failure (severe hypotension, shock including in the context of anaphylactic reaction) may occur in pregnant women with parenteral iron products (such as Venofer) which may cause fetal bradycardia, especially during the second and third trimester. In less advanced cases of iron deficiency, increases in dietary intake of iron may be sufficient. Written by ASHP. Minor/Significance Unknown. Use INFeD only in patients in whom clinical and laboratory investigations have established an iron deficient state not amenable to oral iron therapy. Applies only to oral form of both agents. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling [16.2].) Am J Hosp Pharm. Serious - Use Alternative (1)iron sucrose decreases levels of tetracycline by inhibition of GI absorption. A: Generally acceptable. Minor (2)calcium gluconate decreases levels of iron sucrose by inhibition of GI absorption. This site complies with the HONcode standard for trust- worthy health information: verify here. commonly, these are "non-preferred" brand drugs. Applies only to oral form of both agents. Applies only to oral form of both agents. There are four fields that need to be completed: Weight body weight is used to establish iron deficit and is also taken into account when estimating the iron stores. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. If you have private insurance, Venofer or Monoferric may be on the list of covered medications. Manage and view all your plans together even plans in different states. No data are available regarding overdosage of Venofer in humans. Creating an account is free and takes less than 1 minute. Avoid or Use Alternate Drug. Give each dose as 750mg for a total cumulative dose not to exceed1500mg of ironper course. Venofer must only be administered intravenously either by slow injection or by infusion. Applies only to oral form of both agents. Accessed: 4/12/2011. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Applies only to oral form of both agents. Minor (1)iron sucrose, benazepril. 2010;18(3). Applies only to oral form of both agents. Applies only to oral form of both agents. Injectafer treatment may be repeated if iron deficiency anemia reoccurs. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvdmVub2Zlci1pcm9uLXN1Y3Jvc2UtMzQyMTYy, View explanations for tiers and 1990 Feb;24(2):162-6. Monitor for signs and symptoms of hypotension following each administration of Venofer. 2 *Venofer is an iron replacement product indicated for the treatment of iron deficiency anemia in patients with CKD. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. The following table present normal hemoglobin ranges: There is another equation for iron deficit that can be used to calculate replenishment needs, that of Ganzoni, which takes into account iron stores as well and that can be found in the iron deficit calculator. Applies only to oral form of both agents. iron sucrose decreases levels of methyldopa by inhibition of GI absorption. We have found the lower dose to be better tolerated in the second half of gestation. The usual adult total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Monitor for signs and symptoms of hypotension following each Feraheme infusion. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. The dosing for iron replacement treatment in pediatric patients with Peritoneal or Hemodialysis-Dependent - CKD or Non-Dialysis Dependent CKD have not been established. 3) Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. (1988) Clinical use of the total dose intravenous infusion of iron dextran. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Monitor Closely (1)vitamin E decreases levels of iron sucrose by increasing hepatic clearance. Formula for calculating the required dose of iron sucrose 1. Iron sucrose (Venofer) 100 mg/5 mL vial 200 - 300 mg given every 3-7 days 300 mg doses are given over 90 minutes 500 mg/dose. Monitor Closely (1)lansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Avoid or Use Alternate Drug. LBW = Lean body weight in kg. Applies only to oral form of both agents. This drug is available at a higher level co-pay. Applies only to oral form of both agents. The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Applies only to oral form of both agents. Applies only to oral form of both agents. Administer while the patient is in a reclined or semi-reclined position. didanosine will decrease the level or effect of iron sucrose by increasing gastric pH. 1 ,*. and formulary information changes. Methods: We reviewed the experience of our department between January, 2011 and February, 2014 with the use of intravenous iron sucrose in children 14 years of age who failed in oral iron therapy for iron deficiency anemia (IDA). Applies only to oral form of both agents. Interaction only with oral iron administration. May increase risk of hypotension. On the other hand, slow decreases, such as that in chronic occult gastrointestinal bleeding are often difficult to diagnose. Adding plans allows you to compare formulary status to other drugs in the same class. Administer Venofer early during the dialysis session (generally within the first hour). 2) Koch TA, Myers J, Goodnough LT. (2015) Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. We comply with the HONcode standard for trustworthy health information. Elemental iron product this is a choice between three iron supplement products: Iron dextran 50 mg/mL, Iron sucrose 20 mg/mL and Ferric gluconate 12.5 mg/mL. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling (16.2).] Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. iron sucrose decreases levels of minocycline by inhibition of GI absorption. vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption. Situation Analysis Market Size MAT Sales Cr LC MAT Share % MAT Gr % Total Pharma Market 9388.69 100 13.5 Iron Sucrose 11.18 93.81 37.65 Brand Company Saline MAT . Applies only to oral form of both agents. By clicking send, you acknowledge that you have permission to email the recipient with this information. Use Caution/Monitor. Venofer (iron sucrose) dose calculator | Calculosaurus.com Clinical calculators for obstetrics and gynaecology VTE risk assessment Calculator menu Venofer dose calculator Iron sucrose Not what you were looking for? We'll do this entirely for free, as long as the calculator has applications for women's health. NOTES: Lab and/or medical tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be done while you are using this medication. There is in depth information below the form on the method used and on the result provided. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Fatal reactions have followed the test dose of iron dextran injection. Separate by at least 4 hours. Use Caution/Monitor. The recommended Feraheme dose may be readministered to patients with persistent or recurrent iron deficiency anemia. The cost of Venofer is $145 for a dose of 300 mg and Monoferric is $274 for a dose of 500mg. These can be input in g/dL, g/L or mmol/L. Nutrition. Where C= concentration of elemental iron (mg/ml) in the product being used: Data from Ferrlecit postmarketing spontaneous reports indicate that individual doses exceeding 125 mg may be associated with a higher incidence and/or severity of adverse events, Adult Patients with Hemodialysis Dependent-Chronic Kidney Disease (HDD-CKD), Adult Patients with Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD), WARNING: RISK FOR SERIOUS HYPERSENSITIVITY/ANAPHYLAXIS REACTIONS, Iron Deficiency and Anemia- signs and therapeutic options. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. . It should be recognized that iron storage may lag behind the appearance of normal blood morphology. INFeD is given undiluted at a slow gradual rate not to exceed 50 mg (1 mL) per minute. Use Caution/Monitor. Avoid or Use Alternate Drug. Use Caution/Monitor. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: vitamin products, other iron-containing products. Transferrin saturation (TSAT) values increase rapidly after intravenous administration of iron sucrose; do not perform serum iron measurements for at least 48 hours after intravenous dosing. Iron sucrose: 20 mg/mL. If either is present, do not use the liquid. Anemia caused by the depletion of iron is called iron deficiency anemia. Parenteral iron dextran therapy: a review. Avoid or Use Alternate Drug. May increase risk of hypotension. Contact the applicable plan Diagnosis and management of iron deficiency anaemia: a clinical update. Contraindicated. Monitor Closely (1)iron sucrose decreases levels of methyldopa by inhibition of GI absorption. Observed Hb = the patients current hemoglobin in g/dl. Schrier SL, Mentzer WC, Landaw SA. Use Caution/Monitor. Recommended starting dose 1 Aranesp is dosed at 2.25 mcg/kg SC QW or 500 SC Q3W 1 (SC = subcutaneous) Before initiating 1: Evaluate iron status; administer supplemental iron therapy as needed Correct or eliminate other causes of anemia Initiate 1: Only when Hb < 10 g/dL deferoxamine decreases levels of iron sucrose by inhibition of GI absorption. Treatment of anemia due to iron deficiency. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Applies only to oral form of both agents. 1000 mg. 20 MINUTES. DOSAGE AND ADMINISTRATION: The recommended dose of Feraheme is an initial 510 mg dose followed by a second 510 mg dose 3 to 8 days later. 1996 Aug;11(4):139-46. Minor/Significance Unknown. Dosing: (a) Divide calculated total cumulate dose . OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Applies only to oral form of both agents. Reactions have occurred following the first dose or subsequent doses of Venofer. Venofer [package insert]. The above information is provided for general Applies only to oral form of both agents. Monitor Closely (1)vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption. Serious - Use Alternative (1)iron sucrose decreases levels of gemifloxacin by inhibition of GI absorption. Administer a test INFeD dose prior to the first therapeutic dose. The elemental iron product used is Iron sucrose 20 mg/mL. Minor/Significance Unknown. For patients weighing less than 50 kg (110 lb): Give Injectafer in two doses separated by at least 7 days. Hemoglobin iron deficit = 60 x (14 - 8) x (2.145) = 772 mg iron. Modify Therapy/Monitor Closely. The dosage of Venofer is expressed in mg of elemental iron. deferasirox decreases levels of iron sucrose by inhibition of GI absorption. Iron Deficiency In Pregnancy Calculator, Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator. Intravenous (IV) iron products (use in adults) Dosing information in this table is for adults and includes some dosing recommendations not listed in the approved product information. The iron deficit calculator is useful as one of the determinations performed before iron replenishment therapy is initiated. iron sucrose decreases levels of liothyronine by inhibition of GI absorption. Medicinal forms Volume of iron product required = 25 mL. Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator, Red Blood Cell (RBC) Indices Calculator, Iron Deficiency In Pregnancy Calculator. Administer ciprofloxacin at least 2 hours before or 6 hours after using these products. FOR PATIENTS WEIGHING 50 kg OR MORE: Administer 1000 mg of Monoferric by intravenous infusion 20 minutes as a single dose 1. INFED- iron dextran injection [Package insert], Hemoglobin iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) Note: Hbg (current hemoglobin level) units: (g/dL) Alternatively: Volume of product required (mL) = [weight (kg) x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. The dosing of Monofer was performed according to the Simplified Table as described in section 4.2 above and dosing of iron sucrose was calculated according to Ganzoni and administered as 200 mg infusions. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Monitor Closely (1)omeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Modify Therapy/Monitor Closely. . 2 DOSAGE AND ADMINISTRATION 2.1 Recommended Dosage Recommended dosage for patients weighing 50kg (110lb) or more: Give Injectaferin two doses separated by at least 7 days. Minor/Significance Unknown. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Minor/Significance Unknown.iron sucrose increases levels of calcium acetate by enhancing GI absorption. There is limited experience with administration of an infusion of 500 mg of Venofer, diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14. Minor/Significance Unknown. Alldredge BK, Corelli RL, Ernst ME, Guglielmo BJ, eds. If you log out, you will be required to enter your username and password the next time you visit. Ferric gluconate: 12.5 mg/mL. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin, Do not mix with other medications or add to parenteral nutrition solutions for IV infusion, Do not dilute to concentrations below 1 mg/mL, Add dose to 0.9% NaCl infusion bags (PVC or non-PVC); final concentrations range is 1-2 mg of elemental iron/mL, Visually inspect for particulate matter and discoloration prior to infusion, Stable for 7 days at controlled room temperature (25C).
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